A pair of not-too-bright Mexican cats, one shorter-tempered than the other, decide to chase Speedy Gonzales, the fastest mouse in all Mexico.

The owner of a border town gambling saloon falls in love with a promiscuous young girl. When she has an affair with another, he tosses her out of town. She gets revenge by marrying his younger brother.

Cowboy T-man, Rex Allen, and his partner, Homer Oglethorpe (Buddy Ebsen), go undercover to track down some gold smugglers.

Looking for the killer of his brother, Jack saves the outlaw known as the Mexicali Kid who had collapsed on the desert. Jack joins up with the Kid who leads him to Gorson. Gorson is after a ranch and gets Jack to pose as the heir to the ranch. After the papers are signed he plans to have jack killed. But the Kid recognizes Gorson's henchmen as the men Jack is after and decides to help him.